NANOMEDICINE PIPELINE
MG-GHC24
The 4th generation anti-cancer drug targeting cancer cell metabolism
- Lipid nanoparticle interfering the altered cholesterol homeostasis that promotes tumorigenesis
- Good BBB penetration and targeted accumulation in glioblastoma multiforme (GBM) through receptor-mediated endocytosis
MG-GHC24 INDUCES GBM CELL DEATH
BY DECREASING INTRACELLULAR CHOLESTEROL
THROUGH CHOLESTEROL EFFLUX
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Cytotoxicity
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