NANOMEDICINE PIPELINE

MG-Sh19

Nanomedicine targeting activated microglia in inflammatory contexts
in Alzheimer’s disease

  • A functional peptide-loaded nanoparticle for neuroinflammatory diseases
  • A loading of polypeptide blocking proteins upregulated by microglia in pro-inflammatory CNS into MG-PE3
  • Suppressing pro-inflammatory, neurotoxic microglia and shifting microglia toward a neuroprotective phenotype while keeping clearing Aβ accumulation in Alzheimer’s disease

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